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Epidemiologic studies in the United States have shown increased prevalence of HHV-8 in MSM ranging from 30% to 70% compared with the general population at 4%.8,9 Although this is increased prevalence of HHV-8 is known, it is difficult to quantify the risk MSM without HIV have in KS development compared with the general population because cancer registries do not routinely collect information on sexual orientation and gender identity

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In this regard, precise screenings for personal and family history of thromboembolic events, stroke, and heart disease should be considered prior to therapy initiation (Lee et al., 2016a)

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