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In a randomized controlled trial (RCT) evaluating the weight change using semaglutide, it was also found that after discontinuation of semaglutide, the patients gained weight significantly as well as a significant increase in blood pressure [17], which was a reminder that weight regain may have some adverse effects

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Thirdly, while C3G is a natural flavonoid compound found in various fruits and vegetables and is generally considered safe for consumption as part of a regular diet, excessive intake or long-term use at high doses may pose unknown risks

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