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Visible degradation signs include color changes (yellowing), cloudiness in reconstituted solution, particulate matter, or visible precipitation

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at the beginning of phase 2 it was 3.6, then in the middle of the study it was 5.2 k/mm 3 , so the total white blood cell count fluctuated near the bottom of the reference range during the study, but at no point was the participant either neutropenic or lymphocytopenic