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This proposed mechanism has been directly validated in animal models where the surgically severed vagus nerve attenuated anxiety- and depression-like behaviors in mice after oral antibiotic administration, providing direct evidence for neuropsychiatric effects induced by antibiotics through the gutbrain axis (Joo et al., 2023)

They do not compete for the same receptors

[DOI] [PubMed] [Google Scholar] Steiber A., Kerner J., Hoppel C.L

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So it's just another one in that line