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Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate

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We found that NRF2 promotes the activity of the serine biosynthesis pathway, which is required for the in vitro and in vivo growth of lung cancer cells with high NRF2 activity (DeNicola et al., Nat Genet 2015)

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