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Through a variety of mechanisms, metabolic syndrome increases our risk for cardiovascular disease, which can manifest as both acute and chronic blockages in the arteries supplying blood to our heart, strokes, heart rhythm abnormalities, and heart failure (weakness and stiffness of the heart muscle). The GLP1 [weight loss] drugs are the best available medications for treatment of obesity

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In view of the very poor cure rate with standard excision, some surgeons combine the two methods: surgical excision of the lesion, then three months treatment of the area with imiquimod cream