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While top-line growth remains strong, a deeper dive reveals growing reliance on GLP-1 sales, softening core metrics, and signs of pressure beneath the surface

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However, as presented at the European Association for the Study of Diabetes 2020, with a more modest kidney endpoint comprised of a sustained 40% eGFR decline, a HR of 0.66 was observed (95% CI, 0.50 to 0.88) [42]