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Acylcarnitine profile Metabolites that are abnormal in VLCAD deficiency patients are usually C12, C14, C14:1, C14:2 and C16 [43], with C14:1 accumulation as most important marker, which is derived from partial breakdown of oleic acid (C18:1w9)

Dry eye syndrome (keratoconjunctivitis sicca) is a common eye problem that occurs when the eyes do not produce enough tears or when tears evaporate too quickly, leading to inflammation and damage to the eyes surface

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Safety assessments were conducted from baseline through end-of-study follow-up, and pharmacokinetic and exploratory assessments were performed at prespecified time points, including serial sampling up to 672 h after the final dose

It also helps to maintain tissue integrity and improves the bodys use of antioxidants

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