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If NAC is not provided within 8 hours after APAP intoxication, plasma GST levels will keep increasing and at 4050 hours will be correlated with the time when the major liver damage occurs [48]

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Whether such changes represent a physiological adaptation to overall weight reduction or pose a risk for functional decline remains an unresolved issue [13, 14]

[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Stevenson R.J., Francis H.M