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Glucagon-like peptide-1 (GLP-1)-based therapies, which regulate blood glucose and body weight, show sex-specific effects, with estradiol potentiating their metabolic benefits

Furthermore, the salts of the present invention are well suited for peroral use and do not exhibit any undesired side effects such as pain or necrosis during or after application, in particular, by injection

The common factor is that they dont follow FDA-approved dosing protocol

doi: 10.1016/j.celrep.2019.02.043 73 DaiX-QCamunas-SolerJBriantLJBSantos dosTSpigelmanAFWalkerEMet al

Mendoza N, Galan MI, Molina C, Mendoza-Tesarik R, Conde C, Mazheika M, et al