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Although monthly and less-than-monthly binges also displayed heightened risk estimates, the effect became statistically significant for weekly binge drinking 27

Only one of these, the 8,9-exo-epoxide, appears to be mutagenic and the others are detoxification products

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The MIC nutrients are included for roles in methylation and hepatic lipid handling, while B12 (cobalamin) supports red-blood-cell formation and one-carbon metabolism