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Therapeutic strategies targeting Caspase-3 cleavage of SPTBN1 or modulating nuclear translocation of SPTBN1 cleavage products could mitigate obesity-related metabolic dysregulation (Fig

Recordings were taken from neurons that were pyramidal-like in shape (-20 cell bodies and asymmetric dendrite distribution)

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A 2021 randomised controlled trial in Redox Biology compared oral reduced glutathione (500mg daily) against placebo in healthy adults over eight weeks