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This report describes opposing effects of synaptic compared with extrasynaptic NMDARs on BDNF expression and cell survival: the activation of synaptic NMDARs led to upregulation of BDNF expression and the activation of extra-synaptic NMDARs reduced BDNF expression
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These platforms not only facilitate quick access to healthcare professionals but also offer educational resources that empower patients to take an active role in their health management
(33) provided mechanistic depth by demonstrating that carnitine orotate complex increases carnitine acetyltransferase (CrAT) and -oxidation-related proteins (CPT1, PPAR, UCP2) while inhibiting SREBP1c nuclear translocation and downstream target gene expression ( Hmgcr, Srebp2, Pcsk9, Ldlr ) in HFD-fed mice
biomechanical response to hypertension
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