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SERCA2a, sarcoplasmic/endoplasmic reticulum calcium ATPase 2a

Mechanistically, it activates Nrf2 and its nuclear translocation, thereby enhancing the expression of downstream antioxidant genes to relieve oxidative stress

Furthermore, ACTL6A has been identified as a transcriptional regulator and driving pathways that are of specific benefit to the malignant elements within the tumor 15

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