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The recommend dosing of hydrocortisone to a physiologic level is 10 to 12 mg/m 2 /day in divided doses

A deeper meta-genomic insight to assure 3-D structure/function of nutrient molecules, priming/activation of nutrients with co-factors, compositional stoichiometry, optimal milieu (pH, redox, and ionic strengths), molecular interplay between bioactives (synergism/antagonism), target delivery, ADME/Safety/Toxicity profiles, and most importantly the bio-functional activity, are vital prerequisites in the development of nutrient-based remedials to RESET the virus-induced HMRD in long-COVID, the new onset global metabolic syndrome

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Transient zinc increases may arise from various mechanisms, including efflux from vesicles known as zincosomes, 30 or changes in cellular redox potential facilitated by cytosolic proteins

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Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons