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Arg methylase inhibitors (AMIs), symmetric sulfonated urea, specifically inhibit PRMT activity and, in a rat model, cyclooxygenase-2 (COX-2) expression and suppress inflammation
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doi: 10.1016/j.immuni.2012.04.011 107 ChionhYTCuiJKohJMendenhallIHNgJHJLowDet al
Mast cells are strategically positioned along the body's barrier surfaces, including the gastrointestinal tract, skin, airways, and meninges, where they serve as sentinels of environmental stress 14
Renal effects of N-acetylcysteine in patients at risk for contrast nephropathy: decrease in oxidant stress-mediated renal tubular injury [archive], Nephrol Dial Transplant, 2004;19:18031807 ACT Investigators, Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results from the Randomized Acetylcysteine for Contrast-Induced Nephropathy Trial (ACT) [archive], Circulation, 2011;124:12501259 N-Acetyl Cysteine for Depressive Symptoms in Bipolar DisorderA Double-Blind Randomized Placebo- Controlled Trial, jBiological Psychiatry, Volume 64, Issue 6, Pages 468-475, M
