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Serums or creams containing ingredients like niacinamide, kojic acid, and licorice root extract are effective in targeting melanin production

The KEAP1-NFE2L2 pathway, with the most enriched genes, was selected for further study

A., Doll, M., Campisi, J

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Insoluble material was removed by centrifugation at 40,000 g for 30 min, and the supernatant was incubated with HPC4 resin and 5 mM CaCl 2 overnight at 4 C