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Physical trauma, known as the Koebner phenomenon, can induce the appearance of vitiligo patches in areas of repeated friction, wounds, scars, and pre-existing lesions of contact eczema or psoriasis.76 Exposure to chemicals, such as phenolic derivatives, generates a melanotoxic effect in vitiligo by inducing oxidative stress and causing direct damage to melanocytes

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Therapeutic modulation of the autophagy-mitophagy axis in autoimmune diseases Autophagy inhibition to restrain inflammatory signaling CQ and HCQ represent clinically established autophagy inhibitors with broad immunomodulatory actions

(12) Additionally, higher BMI is strongly correlated with a greater likelihood of surgical site infections, wound dehiscence, venous thromboembolism, and cardiopulmonary events

10.1007/s12035-023-03559-6 114 LankinV

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