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Glutathione is able to prevent damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals

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A 2025 meta-analysis (a study that pools data from multiple trials to find patterns) confirmed this ranking, with retatrutide showing a mean difference of -16.34 kg vs tirzepatide's -11.82 kg vs placebo (J Endocrine Soc, 2025)

It promotes cell migration, reduces systemic inflammation, and upregulates extracellular matrix proteins

If the molecular mass of a polypeptide exceeds 10,000 daltons (10 kg/mol), it is considered a protein