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These moieties are subsequently excreted in the urine 7,8

Antibodies and reagents The following antibodies were used in this study: mouse mAb anti-p150Glued (BD Biosciences 610473, 1:500), mouse mAb anti-pan Akt (Cell Signaling Technology (CST), Frankfurt, Germany

In order to study how the metabolism of APAP affects GSH concentration and resynthesis, we have connected the model depicted in Figure1 to our extant model of glutathione metabolism[9]

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Mdm2 Loss of Heterozygosity Cooperates with Mutant p53 in the Development of Acute Myeloid Leukemia