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Oral GLP-1 pills are not all the same

Some people experience digestive upset from high-dose B12 supplements

The authors thank Marta Rybinska for technical assistance and diet analysis

Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

However, they should be used in conjunction with lifestyle changes, including a healthy diet and regular exercise, for optimal results

However, to date, little research has been conducted on this topic