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and H.G., the Medical Research Council UK (MR/N02589X/1 to S.T.), a British Heart Foundation Postdoctoral Fellowship (FS/IPBSRF/20/27001 to M.K.H.), a Wellcome Trust Sir Henry Dale Fellowship (223279/Z/21/Z to D.B.), and a grant from the European Foundation for the Study of Diabetes Germany (Merck Sharpe Dohme grant to S.T

Furthermore, GLP-1R activation can mitigate liver inflammation and fibrosis by suppressing the NF-B signaling pathway and downregulating pro-inflammatory cytokines like tumor necrosis factor (TNF-) and Interleukin-6 (IL-6) [47, 48]

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Some patients find that anxiety on GLP-1 reflects undiagnosed or undertreated underlying anxiety disorder, making concurrent psychiatric care essential

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