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Compared to other growth factors, compelling evidence suggests that IGF-1 plays a pivotal role in enhancing the regenerative potential of injured tendons

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The direct neurochemical effects on serotonin and dopamine systems mirror the mechanisms of established antidepressants

Additionally, Biochanin A (BCA) can reduce intracellular iron levels by suppressing TfR1 activity and enhancing the expression of ferroportin (FPN), thereby alleviating mitochondrial damage and chondrocyte apoptosis induced by iron overload ( Iron chelators represent an effective intervention for patients with excessive TfR1 expression, binding circulating and intracellular iron for excretion via urine or bile, thereby reducing ferroptosis (Rodrigues de Morais and Gambero, 2019)