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doi: 10.1007/s10067-023-06612-w 47 MitchellPDSalterBMOliveriaJPEl-GammalATworekDSmithSGet al

pluvialis algae naturally contains a complex of carotenoids, including 70% mono-esterified astaxanthin, 10% di-esterified astaxanthin, 5% free astaxanthin, 6% beta-carotene, 5% cantaxanthin and 4% lutein

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Additionally, TLR4 regulates hippocampal neurogenesis and synaptic function through this pathway, and is involved in neuroinflammation and neuronal apoptosis (158)

Multiple biopsies were obtained, and histopathological examination revealed melanosis coli characterised by intracellular pigment accumulation within macrophages