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Consequently, whilst it is clearly a key component in the diet and there may be potential for supplementation to have beneficial effects, evidence to support the administration of tryptophan above and beyond what can be consumed in a healthy diet is currently lacking and further investigation is required

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In the future, we will combine Western blot and immunofluorescence experiments to purposefully elucidate the molecular mechanisms of PI3K, p53, and other candidate pathways in the progression of RRM2 -mediated PTC, providing a more complete theoretical basis

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