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Nakamura K, Oe H, Kihara H, Shimada K, Fukuda S, Watanabe K, Takagi T, Yunoki K, Miyoshi T, Hirata K, Yoshikawa J, Ito H

With respect to the previously mentioned study, this proof-of concept study has important methodological strengths residing in the availability of baseline and post-treatment hepatic biopsies

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This allows the betaine hydrochloride to modulate the stomachs pH in anticipation of the digestion process

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The higher drug level stimulates receptors above their adapted baseline, causing a temporary return of effects like nausea