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Long-Term Considerations and Sustainability Weight loss medications work best as part of a comprehensive approach to obesity management

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NAC and UDCA NAC treatment is found to abrogate acroline-induced hepatotoxicity associated with reduced GSH level, disturbed mitochondrial integrity, endoplasmic reticulum and JNK activation [78]

Additional analyses included measurement of biomarkers such as follicle-stimulating hormone, bone-specific alkaline phosphatase, and creatinine phosphokinase