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GSH deficiency has been identified as an early event in the progression of PD (9)

Transcript-to-transcript correlation analysis of 28032 filtered and normalised transcripts (BioLayout r = 0.85, MCL = 1.7, minimal cluster size = 10 genes) identified 10 clusters of 1115 co-expressed genes, clearly split into two distinct structures (Supplementary Fig

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Additionally, the expression levels of mitochondrial apoptotic proteins such as Bax and cytochrome c (Cyt-c) are significantly increased in T2DM patients

The release and activity of HMGB1 in ferroptosis

Once it neutralizes a free radical, it gets used up and needs to be recycled back into its active state