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Dysesthesia: A New Signal for Retatrutide The TRIUMPH-4 Phase 3 trial revealed an unexpected finding: dysesthesia (abnormal touch sensations where normal sensations feel unusual or painful) in 20.9% of participants on 12 mg and 8.8% on 9 mg, compared to 0.7% on placebo (BioSpace, Dec 2025)

Consumers may benefit from reviewing the FDA's current public guidance on compounded GLP-1 products before making treatment decisions

At 30 mg/mL, 20 units (0.2 mL) delivers 6 mg of tirzepatide

The placebo group lost an average of 2.4%

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Here are the steps to follow: Contact a healthcare provider immediately : The first thing you should do is reach out to your doctor, healthcare provider, or a local poison control center