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A C20 fatty diacid moiety is attached to the lysine residue at position 17 through an AEEA-Glu linker, supporting albumin binding and an extended pharmacokinetic half-life in research models
Key Features Verified 99% Purity HPLC/MS tested for consistent, reproducible results Pulse-Friendly Pharmacology Short-acting profile to model natural GH pulsatility Selective GHRH-R Agonism Designed to engage pituitary somatotroph receptors Timing Experiments Suited for circadian/sleep-aligned release investigations Stack-Compatible Integrates into multi-pathway endocrine and recovery research GMP-Compliant, USA-Made Manufactured for quality and batch-to-batch reliability COA Included Full lot documentation with every vial Mechanism of Action CJC-1295 (No DAC) activates the growth hormonereleasing hormone receptor on anterior pituitary cells, initiating cAMP/PKA signaling that promotes synthesis and pulsatile secretion of GH
What sets CJC-1295 No DAC apart is its extended half-life compared to the DAC version, allowing for less frequent dosing while maintaining consistent results
[DOI] [PubMed] [Google Scholar] Hersch SM, Ferrante RJ
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