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The FDA's 2023 Category 2 designation reflects this gap: there is genuine mechanistic and animal-model evidence, but the human proof-of-concept trials have not been run

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Given the decrease in GPx3 that we observe in konzo affected children, a deeper investigation of possible genetic predispositions is thus warranted, as this has also been a long-standing theory within the research community

6) Spinal Disc Injuries: Herniated Discs and Degenerative Disc Disease: While specific studies on spinal discs are limited, BPC-157s tissue healing properties and ability to promote collagen production suggest potential benefits for disc injuries (1, 16)