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Compared with sham, active stimulation led to significant and sustained improvement on the International Cooperative Ataxia Rating Scale (Cohens d 0.8 post-treatment and 0.9 at three months), with nearly double the responder rate at follow-up

Summary: Vomiting on GLP-1 medications occurs because these drugs slow gastric emptying and stimulate receptors in the brainstem that trigger the vomiting reflex

J Am Coll Nutr 1995

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Of note, the concentration of these four metabolites in the 50 and 35x6 resistant groups was similar to those in the control group ( Figure 1B and Figure 2 )