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Seek emergency care immediately if you experience dark/brown urine with severe muscle pain, as this may indicate rhabdomyolysis, a serious condition requiring urgent treatment

Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation

Patients received subcutaneous injections of BMS-986036 10 mg daily ( n = 25), BMS-986036 20 mg weekly ( n = 23), or placebo ( n = 26) daily for 16 weeks