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However, this would be a rare and specific scenario, not a general concern for most healthy individuals using the medication

Peer review Peer review information Communications Biology thanks Dhaval K Shah and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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They may be less effective at controlling retatrutide-induced heart rate increases because retatrutide does not work through that pathway

Splitting a dose across two syringes introduces extra steps and more opportunities for error

Preclinical studies suggest it supports tissue remodeling and epithelial repair, including recovery from abrasions, lacerations, and other skin injuries