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The IC 50 values for XO inhibition were 9.32 and 10.03 M respectively, being more active than allopurinol (13.03 M)

Researchers introduced 5 cholesterol-conjugated lipophilic chains to P-G3 via covalent linkage to further enhance targeting selectivity and minimize off-target effects

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Low-dose IL-2 reduces IL-21 + T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes