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The article says combination therapy is typically considered when glycemic control is inadequate on GLP-1 monotherapy, or when cost, adherence or side effects favor adding an oral DPP-4 instead of increasing the GLP-1 amount

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11 Defensora socio ambiental, Defensora de Pueblos Indgenas, Defensora de defensores de derechos humanos y periodistas, Informe de visita de campo por informacin sobre desvo de ros y criminalizacin de defensores de derechos humanos en el departamento de Retalhuleu y municipio de Mazatenango del departamento de Suchitepquez, Guatemala, Julio de 2021