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Cancer Res 76(24):71067117

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Accordingly, the cytoprotective effects of NAC or L-NAC against PQ-induced cytotoxicity in A549 human lung adenocarcinoma cells were assessed by measuring cellular PQ uptake, intracellular GSH content, ROS levels, mitochondrial membrane potential, cellular gene expression, inflammatory cytokine release, and cell viability

Alterations in NMDA receptor function can alter the calcium signaling cascade and affect synaptic plasticity, leading to pathophysiological changes in the CNS

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