In ALS models, SOD1 mutations do not markedly alter astrocytic baseline states but lower the threshold for reactivity, which sensitizes astrocytes to oxidative, glutamatergic and inflammatory stress and drives exaggerated reactive responses to otherwise moderate insults 80
In other words, if you are not deficient, adding more B12 does not create an effect, because your body already has what it needs and excretes the excess
Understanding Your Changing Needs As we age and our bodies change, they naturally produce different levels of select vitamins, amino acids, hormones, and more
The Vital Adjuncts: Functional Medicine and Hormone Replacement Therapy GLP-1s are powerful, but they dont operate in isolation
In addition, GLP-1 causes delayed gastric emptying, which leads to weight loss [43]
Chou PJ, Peter, Rebecca Mary BS, Shannar, Ahmad, Pan, Yuxin, Dave, Parv Dushyant M, Xu J