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Balance between on- and off-target effects of the dual GLP1/E agonist, and the concurrence of desensitization at very high doses, might contribute to this phenomenon

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LDH was measured in both the culture medium and cell lysates, and LDH release (%) is expressed as (LDH levels in culture medium)/([LDH levels in culture medium] + [LDH levels in cell lysis]) 100

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