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In order to qualify for the study patients had to be at least 18 years of age with a diagnosis of type 2 diabetes and treated for at least three months with diet and exercise and/or a stable regiment of metformin, as well as an HbA1c level of 7-10% and a body weight of 60-110 kg

Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability