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Results Age-related increased oxidative load in LECs was linked to progressive decline in Nrf2, Cat and Prdx6 expression To identify age-related changes in ROS production and the connection between expression of Prdx6 and its regulator Nrf2, an antioxidant defense pathway, we monitored the intracellular redox-state of primary hLECs of different ages cultured in 96 well plate by using H2-DCF-DA dye 8,43

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Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene

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Systematic review and meta-analysis to estimate the birth prevalence of five inherited metabolic diseases