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TB-500s primary mechanism operates through G-actin sequestration by binding free G-actin monomers, TB-500 promotes cytoskeletal reorganisation that drives cell motility

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While body weight and metabolic phenotypes remain the primary endpoints, the outcome spectrum is progressively extending toward lipotoxic load [e.g., hepatic fat and visceral adipose tissue (VAT)], inflammatory/cardiometabolic risk markers, and reproductive outcomes with higher clinical decision-making value, such as menstruation, ovulation, and pregnancy

J Andrology

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