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As in the previous recommendations by the ADA and EASD (73, 74), life-style intervention (with patient education and motivation, increase of physical activity, and healthy eating) is still in the beginning and center of therapy, followed by pharmacological therapy with metformin (7074)

Metabolomics, 12 , 19

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Rybelsus avoids the cost of pen-injector technology but adds tablet-manufacturing cost, so the totals end up similar

Gazzaniga, F., Stebbins, R., Chang, S