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The safety of daily consumption of this combination depends on the individual's health condition and the doctor's advice

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Vitamin B6 is the most commonly associated with overdose effects when taken in high doses for extended periods

[DOI] [Google Scholar] 33.Quintieri L., Caputo L., Brasca M., Fanelli F

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The required dose is 20 to 40 mg/kg (i.e., 12 g in two divided doses) and significant effects are reported within a period of 3 months.[] ADVERSE EFFECTS ASSOCIATED WITH ORAL PREPARATIONS Local side effects can be expected like soreness of the gums caused by sucking the lozenges