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13 Repeatedly losing and gaining weight (known as weight cycling) is also an independent risk factor for gallstones
These are rare but require immediate attention
Over the past three decades, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) established renin-angiotensin-aldosterone system (RAAS) blockade as the cornerstone of DKD management [7,8]
By focusing on specific receptors in these systems, it helps control hormone responses
However, cross-reactivity is possible, and any switch should be undertaken under specialist supervision with careful monitoring for recurrence of symptoms
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