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Accordingly, it is postulated that the high glutamate concentration in the intestinal microenvironment, which may reach the millimolar range, could prevent inappropriate responses to dietary antigens by exerting immunosuppressive effects on intestinal T cells (178)

Similarly, hyperactivation of the hypothalamicpituitaryadrenal (HPA) axis and aberrant glucocorticoid signaling is critically associated with this disorder

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Vitamin B12 / Lipotropic injections are started through the clinics in-office program

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