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The relationship between B12 and bowel changes is typically indirect, relating more to the supplement formulation, excipients (inactive ingredients), or underlying health conditions rather than the vitamin itself

Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM, Matrisian LM

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Kundu A, Richa S, Dey P, Kim KS, Son JY, Kim HR, Lee SY, Lee BH, Lee KY, Kacew S, Lee BM, Kim HS (2020) Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats

Eli Lilly (LLY +0.87%) just introduced its own pill, trailing slightly behind competitor Novo Nordisk (NVO +1.23%)