10.1080/10715762.2019.1635251 69 LinX.LiS.ZhaoY.MaX.ZhangK.HeX.et al (2013)
The intermediate layer comprises Cas9 complexed with small guide RNA, which is encapsulated within cationic acid-responsive nano-capsules (NCs), which bind to NTAG30 via electrostatic adsorption
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Because this also breaks naturally occurring disulfide bonds within the antibodies, the team next had to reoxidise their antibodies to repair them