Faghfouri AH, Afrakoti LGMP, Kavyani Z, Nogourani ZS, Musazadeh V, Jafarlou M, et al
10.1007/s00198-024-07040-5 83 LiangX.ZhangZ.TianX.CuiQ.LuH.ZhaoM.et al (2024)
Notably, L2HG-induced ferroptosis occurs independently of impaired cystine uptake, transsulfuration pathway activity, or increased GPX4-mediated GSH utilization, revealing a non-canonical ferroptosis mechanism driven by enhanced GSH catabolism
Study participants were age -and sex-matched ( Figure 1B ) and all were infected with the Wuhan strain and recruited at ~12 months post the onset of acute infection ( Supplementary Table 1 )
While your body is generally good at this, the process takes time and energy
In contrast, vitamin A might possess some alarming effects including toxicity to the mitochondria, furthermore decreased life quality and increased morbidity rates have been observed among vitamin A supplement users [82]