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In a mouse model of myocardial infarction, directly transplanted exogenous mitochondria derived from mesenchymal stem cells were better at protecting cardiac function than mitochondria derived from skin fibroblasts

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1998: Wessells et al

Animals expressing igIs 1 [P mec-7 YFPP mec-3 HttQ128::CFP] must be manually selected for CFP expression to avoid silencing of the CFP, which we have not been able to easily reverse (high copy number silencing has been documented 64 )